Stabilized pharmaceutical compositions comprising an HMG-CoA red

Details Stabilized pharmaceutical compositions comprising an HMG-CoA red Stabilized pharmaceutical compositions comprising an HMG-CoA red

1992-12-22

1994-10-18

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514277, 514306, 514415, 514569, 514970, A61K 31505, A61K 31435, A61K 3144, A61K 31405, A61K 3119

Patent

active

053568966

ABSTRACT:
A pharmaceutical dosage form comprising an HMG-CoA reductase inhibitor compound, e.g., fluvastatin sodium, is disclosed which is stabilized against pH-related degradation by an alkaline stabilizing medium capable of imparting a pH of at least 8 to an aqueous solution or dispersion of the composition.

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CA 114 (6) 49589k, Dennick, 1990.

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