Stabilized pharmaceutical

Details Stabilized pharmaceutical Stabilized pharmaceutical

1996-06-21

1998-06-09

Cintins, Marianne M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

A01N 3718, A61K 31165

Patent

active

057634939

ABSTRACT:
This application discloses a method of inhibiting degradation of the antidepressant bupropion hydrochloride in a solid pharmaceutical formulation, so that the pharmaceutical formulation will maintain at least 80% of its initial bupropion potency after one year.

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Walters, Influence of pH on Hydrolytic Decomposition of Diethylopropion Hydrochloride: Stability Studies on Drug--J. of Phar. Sci. vol. 69, No. 10 (1980).

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