Stabilized neutral metalloprotease composition, a method of maki

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

435 681, C12N 996, C12P 2106

Patent

active

057390231

ABSTRACT:
A method for making a stabilized neutral metalloprotease enzyme composition is described in which a neutral metalloprotease and an aqueous solution are combined to obtain a solution or slurry thereof, whereby the stabilized neutral metalloprotease enzyme composition is obtained. The aqueous solution contains an N-protected amino acid, or an N-protected amino acid is added thereto. The invention also provides a stabilized neutral metalloprotease composition, and a method of transporting the stabilized neutral metalloprotease composition.

REFERENCES:
patent: 4116768 (1978-09-01), Isowa et al.
patent: 4165311 (1979-08-01), Isowa et al.
patent: 4521514 (1985-06-01), Oyama et al.
patent: 4883900 (1989-11-01), Keller et al.
patent: 5304470 (1994-04-01), Fischer et al.
Chang et al. (1988) J. Parenteral Sci. Technol., 42(2S), "Parenteral Formulations of Proteins and Peptides: Stability and Stabilizers", pp. S3-S26.
Chemical Abstract, vol. 107, No. 19, 1987, Columbus, Ohio, US, Abstract No. 174422g & JP-A-62029996.
Patent Abstracts of Japan, vol. 012, No. 155 (C-494) 12 May 1988 & JP-A-62 269 689, Nov., 1987.
Database WPI, Week 8609, Derwent Publications Ltd., London, GB; AN 86-059600 & JP-A-61 012 298 (Daiwa Kasei KK) 20, Jan. 1986.
Chemical Abstracts, vol. 117, No. 3, 1991, Columbus, Ohio, Abstract No. 2701v & Biotechnol. Letter, 13(11), 773-8, 1991.
Chemical Abstracts, vol. 103, No. 3, 22 Jul. 1985, Columbus, Ohio, Abstract No. 21136, & Bio/Technology (1985), 3(5), 459-64.
Yang, et al., "Synthesis in Aspartame Precursor: Alpha-L-Aspartyl-L-Phenylalanine Methyl Ester In Ethyl Acetate Using Thermolysin Entrapped In Polyurethane", Biotech. and Bioeng., vol. 32, No. 5, Aug. 20, 1988, pp. 595-603.
"Kinetic Resolution of N-Protected Amino Acid Esters in Organic Solvents Catalyzed by a Stable Industrial Alkaline Protease", Biotechnology Letters vol. 13, No. 11, pp. 773-778 (1991).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Stabilized neutral metalloprotease composition, a method of maki does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Stabilized neutral metalloprotease composition, a method of maki, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stabilized neutral metalloprotease composition, a method of maki will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-633941

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.