Stabilized nanoparticles which may be filtered under sterile con

Details Stabilized nanoparticles which may be filtered under sterile con Stabilized nanoparticles which may be filtered under sterile con

1997-09-09

2000-11-14

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424490, 424496, 424497, 424498, 424501, 424502, A61K 916, A61K 910

Patent

active

061466638

ABSTRACT:
This invention relates to stabilized nanoparticles which may be filtered under sterile conditions, comprising at least one hydrophobic, water-insoluble and non-water-dispersible polymer or copolymer (and optionally an active principle) which is emulsified in an aqueous solution or suspension comprising a phospholipid and a bile salt.

REFERENCES:
patent: 4711895 (1987-12-01), Hazato
patent: 5025004 (1991-06-01), Wu
patent: 5469854 (1995-11-01), Unger
patent: 5500224 (1996-03-01), Vranckx
J. Cont. Release, vol. 30, Apr. 1994, p. 83-94, Schwartz et al., "Solid Lipid Nanoparticles (SLN) for Controlled Drug Delivery . . . ".
Eric Allemann et al., "Drug-Loaded Nanoparticles--Preparation Methods and Drug Targeting Issues," Eur. J. Pharm. Biopharm., 39(5), 173-191 (1993).
Grant & Hack's Dictionary p. 145, 1969.

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