Stabilized naloxone formulations

Details Stabilized naloxone formulations Stabilized naloxone formulations

1996-06-25

1999-02-02

Azpuru, Carlos A.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

514 23, A61F 202, A61K 3170

Patent

active

058661549

ABSTRACT:
Physically and chemically stable pharmaceutical compositions useful for administering naloxone by injection are described. These compositions are essentially aqueous solutions having a pH between 3.0-3.5, and containing naloxone, an acidic or buffer component, a tonicity-adjusting agent, and a stabilizing agent, said composition being optionally sterilized by autoclaving.

REFERENCES:
patent: 4447456 (1984-05-01), Ciganek
patent: 4576930 (1986-03-01), Sugiyama et al.

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