Stabilized microspheres and methods of preparation

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

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436524, 436527, 436528, 436534, 436829, 4284022, 427 211, 427 214, 427 223, G01N 33531, C12Q 100, A61K 3706

Patent

active

056886977

ABSTRACT:
Stabilized microspherical particles having hydrophobic liquid cores prepared as oil-in-water microemulsions. The particles are stabilized by a surface layer comprising an amphiphilic compound and may be functionalized to allow covalent coupling of a ligand to the surface of the particle. When used as tracers in assays, a water insoluble dye may be incorporated in the core liquid of the microparticles.

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patent: 5580735 (1996-12-01), Malick et al.
patent: 5593893 (1997-01-01), Malick et al.
patent: 5620903 (1997-04-01), Malick et al.

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