Stabilized liquid mixtures for labelling nucleic acids

Details Stabilized liquid mixtures for labelling nucleic acids Stabilized liquid mixtures for labelling nucleic acids

1996-03-11

1998-09-29

Weber, Jon P.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

435 6, 435 15, 435 911, 435194, C12N 996, C12N 912, C12Q 168, C12Q 148, C12P 1934

Patent

active

058145028

ABSTRACT:
Stable enzyme compositions are provided in a liquid form for the enzymatic radioactive and non-radioactive labelling of nucleic acids and oligonucleotides. The mixtures preferably contain 30-60% (v/v) glycerin. At a storage temperature between -20 .degree. C. and +4 .degree. C. over a period of at least 12 months, the mixtures do not exhibit any loss of activity.

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patent: 5108892 (1992-04-01), Burke et al.
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patent: 5256555 (1993-10-01), Milburn et al.
Bon Hoa et al. (1973) J. Biol. Chem., 246, 4649-4654.
Weast et al. (1970) CRC Handbook of Chemistry and Physics, 51st Ed., The Chemical Rubber Company, p. D-188.

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