Stabilized liquid enzyme and coenzyme compositions

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving glucose or galactose

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435 17, 435 21, 435 26, 435188, 435190, 435194, C12Q 154, C12Q 150, C12N 996

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active

042502543

ABSTRACT:
Stabilized liquid enzyme and/or coenzyme compositions are prepared for use in biological diagnostic determinations. The compositions contain an enzyme and/or coenzyme, an organic solvent such as a polyol and an aqueous vehicle. The compositions may also contain a polymer and a bacteriostat. The compositions exhibit excellent shelf life and the container in which a composition is stored can be repeatedly opened for use without any substantial degradation of the enzyme and/or coenzyme.

REFERENCES:
patent: 3539450 (1970-11-01), Deutsch
patent: 3540984 (1970-11-01), Deutsch
patent: 3557002 (1971-01-01), McCarty
patent: 3627688 (1971-12-01), McCarty et al.
patent: 3721607 (1973-03-01), Gruber et al.
patent: 3761420 (1973-09-01), Bogardus
patent: 3764478 (1973-10-01), Bergmeyer et al.
patent: 3776900 (1973-12-01), Hammer
patent: 3778350 (1973-12-01), Bergmeyer et al.
George, et al., Stabilization of Lactose and Malate Dehydrogenase By Organic Solvents, Biochem., Biophys. Acta., vol. 191, 1969 pp. 466-468.

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