Stabilized iodine tincture

Details Stabilized iodine tincture Stabilized iodine tincture

1977-10-11

1979-04-24

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Lymphokine

424150, A61K 3179, A61K 3318

Patent

active

041512758

ABSTRACT:
An improved iodine tincture is provided by incorporating therein a small amount, preferably about 0.25 to 2.5 parts, per part by weight of iodine, of povidone, 1-vinyl-2-pyrrolidone polymer. In these proportions , the povidone modified tincture of iodine exhibits markedly reduced tendency to burn or sensitize skin areas on which it dries, is stable, and at the same time retains the essential germicidal activity of unmodified tincture of iodine. The new products can be formulated directly, or as concentrates yielding the improved tincture upon extension with a prescribed amount of aqueous-ethanolic diluent.

REFERENCES:
patent: 1942061 (1934-01-01), Hofmann
patent: 2739922 (1956-03-01), Shelanski
patent: 3028300 (1962-04-01), Cantor et al.
patent: 3898326 (1975-08-01), Cantor et al.
United States Pharmacopeia XIX, p. 259.
Stedman's Medical Dictionary 21st ed., 1968, p. 1647.

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