Stabilized insulin preparations and method for their production

Details Stabilized insulin preparations and method for their production Stabilized insulin preparations and method for their production

1982-03-09

1984-09-18

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

A61K 3726

Patent

active

044723857

ABSTRACT:
Novel pharmaceutical preparations of dissolved insulin having improved physical stability particularly adapted for use in continuous insulin delivery equipment prepared by incorporating therein a calcium or magnesium salt so as to provide a solution containing essentially ionized calcium or magnesium in insulin stabilizing concentrations.
The magnesium or calcium ions concentrations are with the range of about 0.4.times.10.sup.-3 to 10.sup.-2 molar.

REFERENCES:
patent: 2474729 (1949-06-01), Durel et al.
patent: 4196196 (1980-04-01), Tiholiz

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