Stabilized insulin preparations

Details Stabilized insulin preparations Stabilized insulin preparations

1983-02-04

1984-10-09

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

A61K 3726

Patent

active

044761180

ABSTRACT:
Novel pharmaceutical solutions of dissolved insulin having improved physical stability prepared by incorporating therein an essentially ionized zinc salt in a concentration corresponding to a content of zinc ions at the disposal of the insulin of more than 4 Zn.sup.2+ /hexamer insulin preferably 4.2-4.5 Zn.sup.2+ /hexamer insulin. The solutions exhibit a stability factor exceeding 5.
The novel insulin solutions are particularly adapted for use in continuous insulin delivery equipment.

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patent: 2882202 (1959-04-01), Petersen et al.
patent: 2882203 (1959-04-01), Petersen et al.
patent: 3014842 (1961-12-01), Schlichtkrull
patent: 3058885 (1962-10-01), Schlichtkrull
patent: 3091573 (1963-05-01), Schlichtkrull
patent: 3584121 (1971-06-01), Krayenbuhl et al.

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