Stabilized hyaluronan preparations and related methods

Details Stabilized hyaluronan preparations and related methods Stabilized hyaluronan preparations and related methods

2005-05-09

2009-06-09

Lewis, Patrick T (Department: 1623)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C514S023000, C514S062000

Reexamination Certificate

active

07544671

ABSTRACT:
Stabilized hyaluronan preparations wherein hyaluronan is combined with a polyglycol, such as polyethylene glycol. Stabilized hyaluronan preparations of this invention may maintain their viscosity and lubricity for extended time periods (e.g., 2 years) without requiring refrigeration or special storage conditions.

REFERENCES:
patent: 5073545 (1991-12-01), Arima et al.
patent: 5141741 (1992-08-01), Ishida et al.
patent: 6372755 (2002-04-01), Hanamura et al.
patent: 2004/0137079 (2004-07-01), Cook et al.
patent: 2004/0191284 (2004-09-01), Yu et al.
Steckel et al. International Journal of Pharmaceutics (2003), vol. 257, pp. 181-194.

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