Stabilized human tissue plasminogen activator compositions

Details Stabilized human tissue plasminogen activator compositions Stabilized human tissue plasminogen activator compositions

1985-12-17

1988-10-11

Rollins, John

Drug, bio-affecting and body treating compositions

Enzyme or coenzyme containing

Hydrolases

514561, 514970, A61K 37547, A61K 31195

Patent

active

047770430

ABSTRACT:
Disclosed are novel, stable pharmaceutically acceptable compositions containing human tissue plasminogen activator, featuring, for example, an argininum ion containing buffer as a component. Also disclosed are associated means and methods for preparing and using such compositions in various forms.

REFERENCES:
patent: 4552760 (1985-11-01), Murakami et al.
Aoki, Journal Biochem., 75, 731 (1974).
Binder et al., J. Biol. Chem., 254:1998-2003, 1979.

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