Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...
Patent
1985-09-13
1988-11-01
Wiseman, Thomas G.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Stablizing an enzyme by forming a mixture, an adduct or a...
435192, 435 28, 436 15, 436 18, C12N 996, C12N 908, G01N 1300
Patent
active
047820233
ABSTRACT:
An enzyme conjugate composition comprising an enzyme conjugate, a calcium salt and a polyethylene glycol is disclosed. The enzyme conjugate composition is effectively stabilized by the presence of the calcium salt and the polyethylene glycol.
REFERENCES:
patent: 4325832 (1982-04-01), Louderback
patent: 4361652 (1982-11-01), Uemura et al.
Kutuzova et al., Chem. Abst., vol. 94(15) No. 116870d, 1980, "Stabilization of Horseradish Peroxidase in the Presence of Calcium Ions and by Acetylation of the Enzyme".
Eriksson et al., Chem. Abst. vol. 90(17) No. 134538y, 1979, "A Method for the Preparation of Heavy Atom Derivatives of Yeast Cytochrome C Peroxidase".
Middleton, Chem. Abst., vol. 69(25) No. 103698v, 1960, "Preparation and Investigation of a Stabilized Glucose Oxidase Peroxidase Reagent . . . and Polyethylene Glycol".
Anawis Mark A.
Lindberg Roger E.
Abbott Laboratories
Katz Martin L.
Stevenson Robert W.
Teskin Robin L.
Wiseman Thomas G.
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