Stabilized conjugates of uncomplexed subunits of multimeric prot

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

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530418, 530421, 530810, 530815, 530841, 4241931, 4241941, A23J 100, A61K 39385

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active

060720409

ABSTRACT:
The present invention provides methods for preparing, and compositions comprising, stabilized protein-polymer conjugates. More particularly, the present invention relates to the stabilization of individual subunits of multisubunit protein complexes by conjugation to polymers. Such conjugation acts to stabilize the individual subunit in its native conformation in liquid medium, which in turn acts to stabilize its biological activity.

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