Stabilized composition containing creatine kinase and protein ha

Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Stablizing an enzyme by forming a mixture – an adduct or a...

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435194, C12N 996, C12N 912

Patent

active

052178900

ABSTRACT:
A method of stabilizing creatine kinase in a protein solution is disclosed. Sulfhydryl groups in the protein solution are modified and rendered unreactive with creatine kinase. The sulfhydryl groups are blocked with a blocking agent such as cystine.

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Terrence A. Cooper, "The Tools of Biochemistry", (1977), pp. 365-367.
Means and Feeney, Chemical Modification of Proteins, Holden and Day, Inc., (1977), pp. 149-173.

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