Stabilized choline salicylate compounds

Details Stabilized choline salicylate compounds Stabilized choline salicylate compounds

1975-10-24

1977-01-04

Helfin, Bernard

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C 9126

Patent

active

040013111

ABSTRACT:
Choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds of the formula, ##STR1## wherein Me represents the sodium, potassium or lithium ion and R represents the sulfite, bisulfite metabisulfite, dithionate, hydrosulfite and hyposulfite groups are described. Said compounds are stable and inhibit the formation of color in pharmaceutical preparations containing the same. The method for the preparation of choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds, and pharmaceutical dosage forms containing the same are disclosed together with a method for their use to inhibit color formation.

REFERENCES:
patent: 3069321 (1962-12-01), Kahn et al.
patent: 3326760 (1967-06-01), Halpern et al.

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