Stabilized, aqueous, film-forming antimicrobial compositions of

Details Stabilized, aqueous, film-forming antimicrobial compositions of Stabilized, aqueous, film-forming antimicrobial compositions of

1991-05-01

1992-07-14

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

Oxygen or chlorine releasing compound containing

424 62, 424616, A61K 7135, A61K 720, A61K 3340, A61K 3179

Patent

active

051301245

ABSTRACT:
What is provided herein is a stabilized, aqueous, film-forming, antimicrobial composition of hydrogen peroxide. The active, oxygen-generating hydrogen peroxide component in the composition is stabilized in an aqueous-polyol solvent system of predetermined polarity containing PVP. In contrast, similar formulations without PVP experienced a loss of peroxide activity upon standing. Suitably, the composition herein includes about 1-20% by weight hydrogen peroxide, about 0.1-50% by weight PVP, and about 0.1-80% by weight of a polyol, the rest being water. Preferably, about 5-20% by weight of water is present in the composition. Additional solvents may be included therein, such as alcohols, ether oxides, esters, triglycerides of fatty acids, hydrocarbons, N-vinyl lactams, silicone oils, and polyether oligomers.

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