Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form
Patent
1996-05-09
1998-11-03
Levy, Neil S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
424421, 424422, 424484, 424489, 424490, 424602, 424724, A61K 900
Patent
active
058304800
ABSTRACT:
Methods for increasing the biocompatibility of silica-based glass having a concentration of silicon greater than 55%, compositions resulting therefrom, and methods for expeditious formation of calcium-phosphate films on sol-gel derived, silica-based bioactive glass are disclosed.
REFERENCES:
patent: 4871384 (1989-10-01), Kasuga
patent: 5002890 (1991-03-01), Morrison
patent: 5068122 (1991-11-01), Kokubo et al.
patent: 5204106 (1993-04-01), Schepers et al.
patent: 5308764 (1994-05-01), Goodwin et al.
patent: 5433956 (1995-07-01), Patel
patent: 5480844 (1996-01-01), Matsui et al.
patent: 5591453 (1997-01-01), Ducheyne et al.
Cornell et al., "Newest Factors in Fracture Healing", Clin. Orthop., 1992, 227, 297-311.
Ducheyne, P., "Bioglass Coatings and Bioglass Composites as Implant Materials", J. Biomed. Mat. Res., 1985, 19, 273-291.
Li et al., "Apatite Formation Induced by Silica-Gel in a Simulated Body-Fluid", J. Amer. Ceram. Soc., 1992, 75, 2094-2097.
Nicoll et al., "A Novel Xerogel Carrier for Controlled Release of Biologically Active Molecules: III TGF-betal", (Abstract), Trans. Soc. Biomaterials, 1995, 18, 290.
Norden, C.W., "Antibiotic Prophylaxis in Orthopedic Surgery," Rev. Infec. Dis., 1991, 13 (Suppl 10), S842-846.
Pereira et al., "Calcium Phosphate Formation on Sol-Gel-Derived Bioactive Glasses in vitro", J. Biomed. Mat. Res., 1994, 28, 693-698.
Radin et al., "A Novel Xerogel Carrier for Controlled Release of Biologically Active Molecules: I Antibiotics (Vancomycin)", (Abstract), Trans. Soc. Biomaterials, 1995, 18, 289.
"In Vitro Release of Transforming Growth Factor Beta-1 from a Xerogel Carrier", Chapter 6, pp. 121-145.
"In Vitro Cell Bioassay Using Stromal Marrow Cells to Evaluate Si-Ca-P Xerogels with Incorporated Bone Morphogenetic Protein", Chapter 7, pp. 146-162.
Ducheyne Paul
Falaize Sylvie
Radin Shulamith
Santos Erick Manuel
Levy Neil S.
The Trustees of the University of Pennsylvania
LandOfFree
Stabilization of sol-gel derived silica-based glass does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Stabilization of sol-gel derived silica-based glass, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Stabilization of sol-gel derived silica-based glass will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-686758