Stabilization of polypeptide fragments against proteolytic degra

Details Stabilization of polypeptide fragments against proteolytic degra Stabilization of polypeptide fragments against proteolytic degra

1990-04-03

1993-05-18

Brown, Johnnie R.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

435207, 530363, C12N 996

Patent

active

052120813

ABSTRACT:
Enzyme-donor fragments and other unstructured peptides are stabilized against proteolytic degradation by including a mixture of soluble, random-sequence peptides in the assay medium or in the medium in which the enzyme-donor fragment or other peptide is stored.

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Manual of Clinical Laboratory Immunology Rose et al. (1986) pp. 99-109.
Sigma Chemical Company. (1986) pp. 141-145.
Gonnelli, et al., Biochem+Biophys. Res. Comm. (1981) 102:917-923.
Feder et al., Microbiology Abstracts, 14:7, Jul. 1979, London GB, p. 41, "Stabilization of proteolytic enzymes in solution".

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