Stabilization of implantable bioprosthetic devices

Details Stabilization of implantable bioprosthetic devices Stabilization of implantable bioprosthetic devices

2005-03-01

2005-03-01

Saucier, Sandra (Department: 1651)

Chemistry: molecular biology and microbiology

Differentiated tissue or organ other than blood, per se, or...

C623S001100, C623S002130, C623S013110, C623S015120

Reexamination Certificate

active

06861211

ABSTRACT:
The invention relates to methods of stabilizing glycosaminoglycans in a biological tissue (e.g. a bioprosthetic implant) in conjunction with cross-linking of protein in the tissue. The methods of the invention improve the mechanical integrity of the device and improves its stability in vivo. The invention also includes biological tissues having stabilized glycosaminoglycans and cross-linked proteins and kits for preparing such tissues.

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