Stabilization of hydrolysis prone labile organic reagents in liq

Details Stabilization of hydrolysis prone labile organic reagents in liq Stabilization of hydrolysis prone labile organic reagents in liq

1980-11-13

1983-02-08

Gron, Teddy S.

Chemistry: analytical and immunological testing

Including sample preparation

Stabilizing or preserving

435 4, 435 11, 435 13, 435 14, 435 15, 435 16, 435 17, 435 18, 435 19, 435 23, 435 25, 435183, 435188, 436 17, C12N 900, C09K 300, G01N 3348, C12Q 100

Patent

active

043728740

ABSTRACT:
A labile, organic reagent, which is unstable in aqueous media and stable in a nonaqueous media, is stabilized by dissolving the organic reagent in a water-miscible, organic solvent which is liquid at room temperature and which is nondegradatively reactive with the organic reagent to form a solution of the organic reagent in the organic solvent. At least 1% of an inert, high-surface area particulate desiccant is added to the solution for entrapping water with the desiccant so that the residual water content of the solution is below about 0.5%. The desiccant can be removed from the solution before sealing it. More than one organic reagent can be added to the solvent, and a solubilizing agent for the organic reagent can be used.

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