Stabilization of human interferon

Details Stabilization of human interferon Stabilization of human interferon

1993-08-13

1995-07-11

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Lymphokine

Interferon

424 857, 424 855, 424 856, 530351, A61K 4500

Patent

active

054319099

ABSTRACT:
The invention relates to methods for stabilizing human interferon, including pharmaceutical compositions useful in topical applications for the treatment of disorders such as Condyloma acuminata. Amine stabilizing agents such as primary aliphatic amines and anionic stabilizing agents such as lithium organo sulfates protect human interferons from degradation and provide enhanced storage stability. These stabilizing agents containing interferon can be added to appropriate pharmaceutical carriers for topical applications. The topical products also exhibit enhanced storage stability.

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