Stabilization of envelope glycoprotein trimers by disulfide...

Details Stabilization of envelope glycoprotein trimers by disulfide... Stabilization of envelope glycoprotein trimers by disulfide...

2006-09-12

2006-09-12

Parkin, J. S. (Department: 1648)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

C424S208100

Reexamination Certificate

active

07105655

ABSTRACT:
The present application is directed to stabilized envelope glycoprotein trimers. The trimers are stabilized by introducing disulfide bonds at certain sites in the gp41 ectodomain. DNA molecules encoding such trimers can be used to generate an immunogenic reaction.

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