Stabilization of cardiac troponin I subunits and complexes

Details Stabilization of cardiac troponin I subunits and complexes Stabilization of cardiac troponin I subunits and complexes

2006-01-24

2006-01-24

Gitomer, Ralph (Department: 1655)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C424S193100, C424S194100, C435S015000, C530S410000, C530S412000, C530S415000, C530S418000, C530S421000

Reexamination Certificate

active

06989436

ABSTRACT:
The present invention provides methods for preparing, and compositions comprising, stabilized protein-polymer conjugates. More particularly, the present invention relates to the stabilization of individual and complexed subunits of multisubunit protein complexes by conjugation to polymers. Such conjugation acts to stabilize the specific subunit complexes in their native conformation in liquid medium.

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