Src-family kinase and methods of use thereof

Details Src-family kinase and methods of use thereof Src-family kinase and methods of use thereof

1998-01-13

1999-09-14

Wax, Robert A.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Transferase other than ribonuclease

4353201, 435325, 4352523, C12N 912, C12N 120, C12N 1500, C12N 500

Patent

active

059522135

ABSTRACT:
The present invention provides a unique src-family kinase (SFK) that plays a key role in the transformation of early-stage embryonic cells to mesodermal cells. Furthermore, this src-family kinase is likely to be a proto-oncogene. The nucleic acid and amino acid sequences are disclosed.

REFERENCES:
Amaya et al, 1991, Cell, 66:257-70.
Brown and Cooper, 1996, Biochimica et Biophysica Acta. 1287:121-49.
Collett and Steele, 1992, Dev Biol, 152:194-8.
Cornell and Kimelman, 1994, Development, 120:453-62.
Hemmati-Brivanlou, 1995, Nature, 376:331-3.
Jones and Woodland, 1987, Development, 101:557-63.
Kintner and Melton, 1987, Development, 99:311-25.
Klein and Melton, 1994, Endocr Rev, 15:326-41.
Kretzachmar et al, 1997, Nature, 389:618-22.
Labonne and Whitman, 1997, Dev Biol, 183:9-20.
Lagna et al, 1996, Nature, 383:832-6.
Lowenstein et al, 1992, Cell, 70:431-42.
Massague et al, 1997, TICB, 7:187-92.
Mohun et al, 1984,Nature, 311:716-21.
Rozakis-Adcock et al, 1992, Nature, 360:689-92.
Sasai et al, 1994, Cell, 79:779-90.
Smith et al, 1991, Cell, 67:79-87.
Steele, 1985, Nucleic Acids Res, 13:1747-61.
Tanaka et al, 1997, Proc Natl Acad Sci USA, 94:4493-8.
Tang et al, 1995, Cell, 80:473-83.
Theil, 1990, J Biol Chem, 265:4771-4.
Weiss and Littman, 1994, Cell, 76:263-74.
Wright et al, 1990, Development, 109:225-34.
Zeigler et al, 1989, Mol Cell Biol, 9:2724-7.

Affiliated with

Also associated with

Rating

Src-family kinase and methods of use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Src-family kinase and methods of use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Src-family kinase and methods of use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1509324