Squamous cell carcinoma-like immunoreactive antigen from human f

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Separation or purification

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530350, 530395, 530413, 435 723, C07K 302, C07K 320, C07K 1514

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053068114

ABSTRACT:
A squamous cell carcinoma-like (SCC-like) immunoreactive antigen has been identified in human female urine. This material appears to perform the same as and quite likely have the same composition as squamous cell carcinoma associated antigen (SCC) which is a subfraction of tumor antigen 4 (TA-4). This patent also relates to the isolation, and use, of the SCC-like material.

REFERENCES:
Kato, H. et al. (77) Cancer 40:1621-1628.
Cancerlit, Abstract 90058421, Zhau, H. E. et al.: "A 180-KD Protein Marker for Human Bladder Cancer", & J. Urol., 141 (4, Part 2) 318A 1989.
Duffy, T. H. and Bales, R. M., Tumor Markers in Seminal Plasma and Amniotic Fluid, 35 Clin. Chem. (1989) 1079.
Kato, H.; Morioka, H.; Aramaki, S. and Torigoe, T., Radioimmunoassay for Tumor-Antigen of Human Cervical Squamous Cell Carcinoma, 25 Cellular and Molecular Biology (1979) 51-56.
Kato, H.; Morioka, H.; Tsutsui, H.; Aramaki, S. and Torigoe, T., Value of Tumor-Antigen (TA-4) of Squamous Cell Carcinoma in Predicting the Extent of Cervical Cancer, 50 Cancer (1982) 1294.
Kato, H.; Morioka, H.; Aramaki, S.; Tamai, Kind Torigoe, T. Prognostic significance of the tumor antigen TA-4 in squamous cell carcinoma of the uterine cervix, 145 Am. J. Obstet. Gynecol. (1983) 350.
Kato, H.; Tami, K.; Morioka, H.; Nagai, M.; Nagaya, T. and Torigoe, T. Tumor-Antigen (TA-4) in the Detection of Recurrence in Cervical Squamous Cell Carinoma, 54 Cancer (1984) 1544.
Maruo, T.; Shibata, K.; Kimura, A.; Hoshina, M. and Mochizuki, M. Tumor-associated antigen, TA-4, in the monitoring of the effects of therapy for squamous cell carcinoma of the uterine cervix, 56 Cancer (1985) 302.
Morioka, H.; Tumor Antigen (TA-4) of Squamous Cell Carcinoma-Its Tissue Distribution and Its Relationship to Serum TA-4 Concentrations, 6 Asia-Oceania Journal of Obstetrics and Gynecology (1980) 91.

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