Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1988-03-11
1989-09-05
Raymond, Richard L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514278, 514729, 546 17, 546 18, 546150, 568817, 568818, A61K 3147, A61K 31045, C07D21704, C07C 3527
Patent
active
048639320
ABSTRACT:
Azadecalins and C-7 substituted decalins with squalene oxide cyclase inhibitory activity are useful as inhibitors of cholesterol synthesis and hence may be used in pharmaceuticals for regulating cholesterol levels in a mammal.
REFERENCES:
Gaspert, et al., "Chemical Abstracts", vol. 52, 1958, col. 11797g.
Sondheimer, et al., "J.A.C.S.", vol. 80, 1958, pp. 1967-1971.
Sinensky Michael
Spencer Thomas A.
Cooper Iver P.
Dartmouth College
Raymond Richard L.
Somatogenetics International, Inc.
Turnipseed James H.
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