Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2000-12-08
2009-08-18
Silverman, Eric E. (Department: 1618)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
Reexamination Certificate
active
07575761
ABSTRACT:
The present invention provides exemplary systems and methods for producing dry powder formulations. In one embodiment, a system (10) includes at least one conditioning zone (12) having an inlet (20) to introduce an atomized formulation (18) into the conditioning zone. A controller (14, 16) controls temperature and relative humidity of the airflow into the conditioning zone to allow amorphous-to-crystalline transformation of the atomized formulation. In another embodiment, the formulation is suspended in the conditioning zone for a residence time of sufficient duration to allow surface orientation of surface active components. A dryer (24) is coupled to the conditioning zone to dry the atomized formulation, and a collector (28) collects the formulation in powder form.
REFERENCES:
patent: 3770207 (1973-11-01), Muller et al.
patent: 3790079 (1974-02-01), Berglund et al.
patent: 3825188 (1974-07-01), Doering
patent: 3956009 (1976-05-01), Lundquist et al.
patent: 4035317 (1977-07-01), Gershberg
patent: 4052255 (1977-10-01), Hackbarth et al.
patent: 4127235 (1978-11-01), Klaile et al.
patent: 4221339 (1980-09-01), Yoshikawa
patent: 4261793 (1981-04-01), Nakamura et al.
patent: 4486435 (1984-12-01), Schmidt et al.
patent: 4540602 (1985-09-01), Motoyama et al.
patent: 4590206 (1986-05-01), Forrester et al.
patent: 4702799 (1987-10-01), Tuot
patent: 4721709 (1988-01-01), Seth et al.
patent: 4748034 (1988-05-01), de Rham
patent: 4760093 (1988-07-01), Blank et al.
patent: 4784878 (1988-11-01), Haak
patent: 4794167 (1988-12-01), Lindner et al.
patent: 4818424 (1989-04-01), Evans et al.
patent: 4835187 (1989-05-01), Reuter et al.
patent: 4871489 (1989-10-01), Ketcham
patent: 4952402 (1990-08-01), Sparks et al.
patent: 5000888 (1991-03-01), Kilbride, Jr. et al.
patent: 5009367 (1991-04-01), Nielsen
patent: 5017372 (1991-05-01), Hastings
patent: 5026550 (1991-06-01), Aeschbach et al.
patent: 5064501 (1991-11-01), Boersen
patent: 5221731 (1993-06-01), Weymans et al.
patent: 5260306 (1993-11-01), Boardman et al.
patent: 5269980 (1993-12-01), Levendis et al.
patent: 5279708 (1994-01-01), Wood et al.
patent: 5384133 (1995-01-01), Boyes et al.
patent: 5482927 (1996-01-01), Maniar et al.
patent: 5518709 (1996-05-01), Sutton et al.
patent: 5580856 (1996-12-01), Prestrelski et al.
patent: 5607697 (1997-03-01), Alkire et al.
patent: 5622657 (1997-04-01), Takada et al.
patent: 5624530 (1997-04-01), Sadykhov et al.
patent: 5628937 (1997-05-01), Oliver et al.
patent: 5648096 (1997-07-01), Gander et al.
patent: 5651990 (1997-07-01), Takada et al.
patent: 5667806 (1997-09-01), Kantor
patent: 5687905 (1997-11-01), Tsai
patent: 5716558 (1998-02-01), Nielsen et al.
patent: 5723269 (1998-03-01), Akagi et al.
patent: 5741478 (1998-04-01), Osborne et al.
patent: 5776491 (1998-07-01), Allen, Jr. et al.
patent: 5800598 (1998-09-01), Chein et al.
patent: 5807576 (1998-09-01), Allen, Jr. et al.
patent: 5855913 (1999-01-01), Hanes et al.
patent: 5874064 (1999-02-01), Edwards et al.
patent: 5924216 (1999-07-01), Takahashi
patent: 5957848 (1999-09-01), Sutton et al.
patent: 5976574 (1999-11-01), Gordon
patent: 5981474 (1999-11-01), Manning et al.
patent: 5985248 (1999-11-01), Gordon et al.
patent: 5985309 (1999-11-01), Edwards et al.
patent: 5993805 (1999-11-01), Sutton et al.
patent: 5997848 (1999-12-01), Patton et al.
patent: 6001336 (1999-12-01), Gordon
patent: 6015546 (2000-01-01), Sutton et al.
patent: 6017310 (2000-01-01), Johnson et al.
patent: 6022525 (2000-02-01), Sutton et al.
patent: 6051256 (2000-04-01), Platz et al.
patent: 6051257 (2000-04-01), Kodas et al.
patent: 6077543 (2000-06-01), Gordon et al.
patent: 6117455 (2000-09-01), Takada et al.
patent: 6136295 (2000-10-01), Edwards et al.
patent: 6149941 (2000-11-01), Schwarz et al.
patent: 6174469 (2001-01-01), Ganan-Calvo
patent: 6197835 (2001-03-01), Ganan-Calvo
patent: 6223455 (2001-05-01), Chickering, III et al.
patent: 6258341 (2001-07-01), Foster et al.
patent: 6290991 (2001-09-01), Roser et al.
patent: 6308434 (2001-10-01), Chickering, III et al.
patent: 6316029 (2001-11-01), Jain et al.
patent: 6331290 (2001-12-01), Morgan
patent: 6331310 (2001-12-01), Roser et al.
patent: 6365190 (2002-04-01), Gordon et al.
patent: 6383810 (2002-05-01), Fike et al.
patent: 6416739 (2002-07-01), Rogerson et al.
patent: 6423344 (2002-07-01), Platz et al.
patent: 6451349 (2002-09-01), Robinson et al.
patent: 6503480 (2003-01-01), Edwards et al.
patent: 6560897 (2003-05-01), Chickering, III et al.
patent: 6565885 (2003-05-01), Tarara et al.
patent: 6572893 (2003-06-01), Gordon et al.
patent: 6582728 (2003-06-01), Platz et al.
patent: 6592904 (2003-07-01), Platz et al.
patent: 6656492 (2003-12-01), Kajiyama et al.
patent: 2002/0071871 (2002-06-01), Snyder et al.
patent: 2002/0081266 (2002-06-01), Woolfe et al.
patent: 2002/0175225 (2002-11-01), Boersen et al.
patent: 2003/0124193 (2003-07-01), Snyder et al.
patent: 2003/0203036 (2003-10-01), Gordon et al.
patent: 2003/0215514 (2003-11-01), Platz et al.
patent: 0072046 (1983-02-01), None
patent: 0344375 (1989-12-01), None
patent: 0408801 (1991-01-01), None
patent: 0461930 (1991-12-01), None
patent: 469725 (1992-02-01), None
patent: 512693 (1992-11-01), None
patent: 0611567 (1994-08-01), None
patent: 628331 (1994-12-01), None
patent: 681843 (1995-11-01), None
patent: 709085 (1996-05-01), None
patent: 972526 (2000-01-01), None
patent: 1004349 (2000-05-01), None
patent: 473471 (1937-10-01), None
patent: 621785 (1949-04-01), None
patent: 1112553 (1968-05-01), None
patent: 2105189 (1983-03-01), None
patent: WO 88/07870 (1988-10-01), None
patent: WO 90/11139 (1990-10-01), None
patent: WO 91/16882 (1991-11-01), None
patent: WO 94/08627 (1994-04-01), None
patent: WO 94/20204 (1994-09-01), None
patent: WO 95/13864 (1995-05-01), None
patent: WO 95/23613 (1995-09-01), None
patent: WO 95/24183 (1995-09-01), None
patent: WO 95/31479 (1995-11-01), None
patent: WO 96/03978 (1996-02-01), None
patent: WO 96/05809 (1996-02-01), None
patent: WO 96/09814 (1996-04-01), None
patent: WO 96/11580 (1996-04-01), None
patent: WO 96/15814 (1996-05-01), None
patent: WO 96/32096 (1996-10-01), None
patent: WO 97/28788 (1997-08-01), None
patent: WO 97/36574 (1997-10-01), None
patent: WO 97/36578 (1997-10-01), None
patent: WO 97/41833 (1997-11-01), None
patent: WO 97/44067 (1997-11-01), None
patent: WO 98/01228 (1998-01-01), None
patent: WO 98/29096 (1998-07-01), None
patent: WO 98/29098 (1998-07-01), None
patent: WO 98/31346 (1998-07-01), None
patent: WO 98/36888 (1998-08-01), None
patent: WO 98/47493 (1998-10-01), None
patent: WO 99/16419 (1999-04-01), None
patent: WO 99/16422 (1999-04-01), None
patent: WO 99/17742 (1999-04-01), None
patent: WO 99/30834 (1999-06-01), None
patent: WO 99/31019 (1999-06-01), None
patent: WO 99/32083 (1999-07-01), None
patent: WO 00/00176 (2000-01-01), None
patent: WO 00/09084 (2000-02-01), None
patent: WO 00/10541 (2000-03-01), None
patent: WO 00/12278 (2000-03-01), None
patent: WO 00/13668 (2000-03-01), None
patent: WO 00/66256 (2000-11-01), None
patent: WO 00/76673 (2000-12-01), None
patent: WO 01/03673 (2001-01-01), None
patent: WO 01/13885 (2001-03-01), None
patent: WO 01/15664 (2001-03-01), None
patent: WO 01/45731 (2001-06-01), None
patent: WO 01/49263 (2001-07-01), None
patent: WO 01/64188 (2001-09-01), None
patent: WO 01/87278 (2001-11-01), None
patent: WO 02/09669 (2002-02-01), None
patent: WO 02/15876 (2002-02-01), None
patent: WO 02/15880 (2002-02-01), None
patent: WO 02/078675 (2002-10-01), None
patent: WO 03/000202 (2003-01-01), None
Carpenter, John F. et al., “Modes of Stabilization of a Protein by Organic Solutes During Desiccation,” Cryobiology. 1988. vol. 25, pp. 459-470.
He et al., “Chitosan Microspheres Prepared by Spray Drying,” International J. of Pharm. (Amsterdam), vol. 187, No. 1, o. 53-65 1991.
Hino et al., “Development of a new type nozzle and spray-drier for industrial production of fine powders”, European J. of Pharmaceutics and Biopharmaceutics (2000), vol. 49, pp. 79-85.
Masters, “The Process Stages if Spray Drying: Atomization”, Sp
Bennett David B.
Brewer Thomas K.
Platz Robert M.
Snyder Herman
Mazza Michael J.
Novartis Pharma AG
Silverman Eric E.
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