Spray-drying method for preparing liposomes and products produce

Details Spray-drying method for preparing liposomes and products produce Spray-drying method for preparing liposomes and products produce

1985-02-11

1989-05-16

Robinson, Douglas W.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 264 43, 264 46, 4284022, 424417, A61K 3722, A01N 2526, A61J 500, B32B 902

Patent

active

048308587

ABSTRACT:
A method is provided for preparing a stable liposome precursor in the form of a mixture of spray-dried liposomal components including one or more biologically active compounds which may be stored dry and reconstituted with water to form a liposomal preparation immediately prior to use. The dry liposome precursor is also provided.

REFERENCES:
patent: 4229360 (1980-10-01), Schneider et al.
patent: 4247411 (1981-01-01), Vanlerberghe et al.
patent: 4311712 (1982-01-01), Evans et al.
patent: 4485054 (1984-11-01), Mezel et al.
patent: 4508703 (1985-04-01), Redziniak et al.
Ryman, B. E., "The Use of Liposomes as Carriers of Drugs and Other Cell-Modifying Molecules," Proc. 6th Int'l Congr. Pharmacol. 5, 91, (1976) published in Drug Applications, Clinical Pharmacology, vol. 5, pp. 91-103, Pergamon Press (1975).

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