Spoiiie

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...

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536 231, 536 237, 4352523, 435 693, 4353201, 435365, 435325, 435362, 435367, 43525233, 935 66, 935 71, 935 72, 935 12, 935 22, C07H 2104, C12N 1531, C12N 1563

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058887709

ABSTRACT:
The invention provides spoIIIE polypeptides and DNA (RNA) encodig spoIIIE polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utlizng spoIIIE polypeptides to screen for antibacterial compounds.

REFERENCES:
Foulger, et al., GenBank Submission, Accession No. S09411: A32269; "The role of the sporulation gene spo111E in the regulation of prepore-specific gene expression in Bacillus Subtilis.", Nov. 21, 1993.
Sharpe, et. al. "Post septational chromosome partitioning in bacteria." Proc. Nalt. Acad. Science. vol. 92, pp. 8630-8634, September, (1995).
Wu, et. al., "Septal localization of the SpolllE chromosome partitioning protein in Bacillus subtilis" The EMBO Journal, vol. 16, No. 8, pp. 2161-2169, (1997).
Wu, et al., "A conjugation-like mechanism for prespore chromosome partitioning during sporulation in Bacillus subtilis." Genes & Development Vpl. 9, pp. 1316-1326, (1995).
Begg, et. al., "A new Eschrichia coli Cell Division gene, ftK." Journal of Bacteriology, vol. 177, No. 21, pp. 6211-6222, (1995).
Butler, et. al., "Nucleotide Sequence of the Sporulation Operon, soplllE, of Bacillus subtilis." Journal of General Macribiology vol. 133, pp. 2359-2370, (1987).
Foulger, et al., GenBank Submission, Accession No. B32269, The role of the Sporulation Gene SpolllE in the regulation of prepore specific gene expression in Bacillus subtilis, 1997.

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