Splicing variant of the epstein-barr virus-induced G-protein cou

Details Splicing variant of the epstein-barr virus-induced G-protein cou Splicing variant of the epstein-barr virus-induced G-protein cou

1998-10-26

1999-12-14

Eisenschenk, Chris

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

435 72, 435 691, 435 693, 435 701, 435 711, 4241851, G01N 3353, C07K 1400, A61K 3800

Patent

active

060019727

ABSTRACT:
EBI 3 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing EBI 3 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia, bulimia, asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.

REFERENCES:
Birkenbach et al. "Epstein-Barr Virus-Induced Genes: First Lymphocyte-specific G Protein-Coupled Peptide Receptors", Journal of Virology, vol. 67, pp. 2209-2220 (1993).
GenBank Accession No. L08176.
Sequence Comparison (3/98).

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