Splicing variant of the Epstein-Barr virus-induced G-protein cou

Details Splicing variant of the Epstein-Barr virus-induced G-protein cou Splicing variant of the Epstein-Barr virus-induced G-protein cou

1997-07-29

1999-02-23

Knode, Marian C.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

435 701, 435 711, 435 691, 4352402, 4352523, 4352542, 4353201, 536 231, 514 441, C12N 1511, C12N 1563, C12N 121, A61K 4800

Patent

active

058742522

ABSTRACT:
EBI 3 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing EBI 3 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parkinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; astma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dysldnesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.

REFERENCES:
Sequence Comparison, Mar. 1998.
Accession No. L08176.
Birkenbach, M., et al., "Epstein-Barr Virus-Induced Genes: First Lymphocyte-specific G Protein-Coupled Peptide Receptors", Journal of Virology (67):2209-2220 (1993).

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