Spironolactone-containing composition and use thereof

Details Spironolactone-containing composition and use thereof Spironolactone-containing composition and use thereof

1984-04-03

1986-04-15

Roberts, Elbert L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

A61K 3158

Patent

active

RE0321125

ABSTRACT:
A composition containing spironolactone in an amount effective to suppress excess androgenic activity. The spironolactone-containing composition is applied directly to the skin site afflicted with excess androgens.

REFERENCES:
patent: 3257390 (1966-06-01), Patchett
Shapiro et al., "Journal of Clinical Endocrinology and Metabolism, 51; p. 429 (1980).
Boisselle et al., "Fertility and Sterility; vol. 32, No. 3, Sep. 1979, pp. 276-279.
Ober et al., "Annals of Internal Medicine" 89 No. 5 (Part 1) Nov. 1978, pp. 543-544.
Chem. Abst. 83(21) 172,881t, An Abstract of the Publication in "Endocrinology", 97(1) pp. 52-58.

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