Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1974-09-09
1977-01-18
Goldberg, Jerome D.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
424240, A61K 3171
Patent
active
040039960
ABSTRACT:
The administration of aldosterone inhibitors of the spirolactone structural type prior to and during treatment with anti-neoplastic agents such as adriamycin results in retention of the desired activity of the latter substances while inhibiting their undesirable cardiotoxic properties.
REFERENCES:
lefrak et al., Cancer, vol. 32, Aug. 1973, pp. 302-314.
O'Bryan et al., Cancer, vol. 32, July 1973, pp. 1-8.
Chemical Abstracts 73: 21854d (1970).
Pappo Raphael
Polk Rothwell
G. D. Searle & Co.
Goldberg Jerome D.
McDonnell John J.
Schubert Elliot N.
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