Spirodilactams

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

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548410, 548147, 548336, 548374, 548247, 548249, 548216, 546 15, C07D27300, C07D49100, C07D40300, C07D48700

Patent

active

051030012

ABSTRACT:
Novel 1,6-diaza [4.4] spirodilactams having heterocyclic-containing substituents on each spiro ring nitrogen atom are produced by reaction of a heterocyclic-substituted primary amine compound and a spirodilactam precursor selected from 4-oxoheptanedioic acid compounds or 1,6-dioxaspiro[4.4]nonane-2,7-dione compounds. The substituted spirodilactam products have a plurality of heterocyclic rings and are useful in biological applications and as stabilizers.

REFERENCES:
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patent: 4939251 (1990-07-01), Wang
patent: 4946858 (1990-08-01), Wrobel
Pariza et al., "An Improved Procedure for the Synthesis of 4-oxopimelate-derived materials", Synthetic Comm., 13(3), 243-254 (1983).
Cava et al., J. Am. Chem. Soc., 79, 1706-1709 (1959).

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