Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-08-26
2000-01-18
Higel, Floyd D.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
514409, 514424, 548409, 548410, 548542, C07D20996, C07D20954, C07D49100, C07D49500, A61K 3140
Patent
active
06015912&
ABSTRACT:
The invention provides compounds of formula ##STR1## as described in the claims, or an optical isomer, diastereomer or enantiomer thereof, or a pharmaceutically-acceptable salt, or biohydrolyzable amide, ester, or imide thereof are useful as inhibitors of metalloproteases.
Also disclosed are pharmaceutical compositions and methods of treating diseases, disorders and conditions characterized by metalloprotease activity using these compounds or the pharmaceutical compositions containing them.
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Almstead Neil Gregory
Bradley Rimma Sandler
De Biswanath
Natchus Michael George
Pikul Stanislaw
Higel Floyd D.
Rasser Jacobus C.
Roof Carl J.
Suter David L.
The Procter & Gamble & Company
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