Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-03-01
1993-06-15
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546 17, C07D22120, A61K 3144
Patent
active
052198600
ABSTRACT:
A class of spirocyclic piperidine derivatives are selective ligands at sigma recognition sites and are therefore useful in the treatment and/or prevention of psychiatric disorders.
REFERENCES:
patent: 3125580 (1964-03-01), Janssen
Reimann et al "Synthese von 3,4-dihydro . . . " Arch. Pharm. 320(5) 385-393 (1987).
Reimann et al "Synthese und pharmakcologische . . . " Arch. Pharm. 323(1) 35-39 (1990) (Jan. 1990).
Hashigaki et al "Synthesis and structure . . . " Chem. Pharm. Bull 32(9) 3561-8 (1984).
Hackh "Chemical Dictionary" p. 331, 1983.
Billington David C.
Chambers Mark S.
Chang Celia
DiPrima Joseph F.
Ivy C. Warren
Merck Sharp & Dohme Limited
North Robert J.
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