Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1997-03-13
1998-06-02
Grumbling, Matthew V.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
514212, 514326, 514364, 514365, 514385, 514403, 514396, 514409, 514406, 514256, 514255, 514278, 540543, 548147, 5483007, 548408, 548216, 5483575, 548131, 546 16, 546256, 546255, 5462687, A61K 3154, A61K 31535, C07D40114, C07D40314
Patent
active
057600295
ABSTRACT:
This invention relates to novel heterocycles, including antagonists of the .alpha..sub.v .beta..sub.3 integrin and related cell surface adhesive protein receptors, to pharmaceutical compositions containing such compounds, processes for preparing such compounds, and to methods of using these compounds, alone or in combination with other therapeutic agents, for the inhibition of cell adhesion, the treatment of angiogenic disorders, inflammation, bone degradation, cancer metastasis, diabetic retinopathy, thrombosis, restenosis, macular degeneration, and other conditions mediated by cell adhesion and/or cell migration and/or angiogenesis.
Jadhav Prabhakar Kondaji
Smallheer Joanne Marie
Ferguson Blair Q.
Grumbling Matthew V.
The DuPont Merck Pharmaceutical Company
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