Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-04-24
2011-10-04
Rao, Deepak (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S337000, C514S338000, C514S339000, C514S365000, C514S374000, C544S310000, C544S311000, C544S312000, C548S181000, C548S235000
Reexamination Certificate
active
08030322
ABSTRACT:
The present invention relates to compounds of formula (I) or salts thereofwherein A, X, R2, R4and n are defined herein, processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, as modulators of dopamine D3receptors, e.g., to treat drug dependency, as antipsychotic agents, to treat obsessive compulsive spectrum disorders, premature ejaculation or to enhance cognition.
REFERENCES:
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Layzer, Degenerative Diseases of the Nervous System, Cecil Textbook of Medicine, 20thEdition, vol. 2, pp. 2050-2057, 1996.
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Rice, M.L. et al: “Spirans. XVII. Spirans derived from 4-chromanone” Journal of Heterocyclic Chemistry, Provo, UT, US. vol. 8, No. 1, 1971, pp. 155-156.
Bertani Barbara
Di Fabio Romano
Micheli Fabrizio
Pasquarello Alessandra
Tarsi Luca
Deppenbrock Bonnie L.
Glaxo Group Limited
Rao Deepak
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