Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Bacterium or component thereof or substance produced by said...
Patent
1980-01-25
1981-08-18
Jiles, Henry R.
Drug, bio-affecting and body treating compositions
Nonspecific immunoeffector, per se ; or nonspecific...
Bacterium or component thereof or substance produced by said...
42424857, 424250, 424267, 424274, 26032634, 26032636, 2603265S, 2603265CA, 2603265SF, 26034622, 26034671, 26034673, 544153, 544376, 546196, A61K 3134
Patent
active
042846447
ABSTRACT:
Novel spiro compounds of the formula: ##STR1## wherein Ring A represents a benzene ring or a naphthalene ring, said rings being unsubstituted or substituted by at least one of lower alkyl, nitro, halogen, amino which may optionally be substituted, hydroxyl which may optionally be substituted, acyl, sulfamoyl, carboxyl, lower alkoxycarbonyl, carbamoyl which may optionally be substituted, ureido which may optionally be substituted, thioureido which may optionally be substituted, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, aminomethyl which may optionally be substituted, cyano and phenyl, have gastric secretion inhibitive, anti-inflammatory and analgesic activities, and are of value as drugs.
REFERENCES:
patent: 4105670 (1978-08-01), Noguchi et al.
Okitsu et al., Heterocycles, vol. 6, No. 11 (1977), pp. 1877-1879.
Donnelly et al., Chem. and Industry (1967), pp. 1402-1403.
Imada Isuke
Kawada Mitsuru
Sugihara Hirosada
Watanabe Masazumi
Dentz Bernard
Jiles Henry R.
Takeda Chemical Industries Ltd.
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