Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors

Details Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors Spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors

2005-01-11

2005-01-11

Raymond, Richard L. (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C544S300000, C544S301000

Reexamination Certificate

active

06841671

ABSTRACT:
The present invention relates to 5-spiro-pyrimidine-2,4,6-trione metalloproteinase inhibitors of the formulawherein said “A” is a 5-7 membered heterocyclic ring as defined in the specification and to pharmaceutical compositions and methods of treating inflammation, cancer and other disorders.

REFERENCES:
patent: 3714093 (1973-01-01), Wolf et al.
patent: WO 9858925 (1998-12-01), None
patent: WO 0047565 (2000-08-01), None
patent: WO 0112611 (2001-02-01), None
USPTO Classification Definitions Re Heterocyclic 1985 Streitwieser et al., Introduction of Organic Chemistry 2nd Ed (1981) p. 1061 MacMillan Pub. Acheson “An Introduction to the Chemistry of Heterocyclic Compounds” (1976) p. 1 John Wiley Pub.*
PCT International Search Report, PCT/IB01/01986, 2001.

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