Spiro-pyridazines and analogs thereof useful as aldose reductase

Details Spiro-pyridazines and analogs thereof useful as aldose reductase Spiro-pyridazines and analogs thereof useful as aldose reductase

1990-10-11

1992-01-14

Shah, Mukund J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D48710

Patent

active

050812416

ABSTRACT:
This invention relates to spiro-pyridazines, to processes for their preparation, to methods for using the compounds, and to pharmaceutical prepartions thereof. The compounds have pharmaceutical properties which render them beneficial for the prevention or treatment of diabetes mellitus associated complications.

REFERENCES:
patent: 4855298 (1989-08-01), Yamada et al.
patent: 4927831 (1990-05-01), Malamas

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