Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-07-18
2006-07-18
Saeed, Kamal A. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S274400, C514S341000
Reexamination Certificate
active
07078420
ABSTRACT:
Compounds having the formula (I), and pharmaceutically-acceptable salts, hydrates, enantiomers, and diastereomers, and prodrugs thereof,are useful as inhibitors of LFA-1/ICAM and as anti-inflammatory agents, wherein L and K are O or S; Z is N or CR4b; Ar is an optionally-substituted aryl or heteroaryl; G is a linker attached to T or M or is absent; J, M and T are selected to define a three to six membered saturated or partially unsaturated non-aromatic ring; and R2, R4a, R4b, and R4care as defined in the specification.
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Dhar T. G. Murali
Iwanowicz Edwin J.
Launay Michele
Maillet Magali Jeannine Blandine
Nicolai Eric Antoine
Bristol--Myers Squibb Company
Cerep SA
Coppins Janet L
Duncan Laurelee A.
Saeed Kamal A.
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