Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-12-04
2007-12-04
Aulakh, Charanjit S. (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S015000, C546S116000, C546S167000, C544S182000, C544S331000, C544S332000, C544S336000, C548S311400, C548S364400, C549S265000, C514S275000, C514S397000
Reexamination Certificate
active
10922869
ABSTRACT:
Compounds represented by the general formula (I)wherein Ar1represents an aryl or heteroaryl which may be substituted; n represents 0 or 1; T, U, V and W each independently represent a nitrogen atom or a methine group which may have a substituent selected from the group consisting of halogen, lower alkyl, hydroxy and lower alkoxy, wherein at least two of which represent said methine group; X represents methine, hydroxy substituted methine or nitrogen atom; Y represents an imino which may be substituted with lower alkyl, or oxygen; and a salt, ester or N-oxide derivative thereof. The compounds exhibit NPY antagonistic activities and are useful as agents for the treatment of various diseases related to NPY, for example, cardiovascular disorders, central nervous system disorders, metabolic diseases, sexual and reproductive dysfunctions, gastro-intestinal disorders, respiratory disorders, inflammation or glaucoma, and the like.
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Chiba Masato
Fukami Takehiro
Haga Yuji
Ishihara Akane
Ishii Yasuyuki
Aulakh Charanjit S.
Banyu Pharmaceutical Co. Ltd.
Wenderoth , Lind & Ponack, L.L.P.
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