Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...
Patent
1977-12-06
1979-11-13
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Conjugate or complex of monoclonal or polyclonal antibody,...
Conjugated via claimed linking group, bond, chelating agent,...
536 17R, A61K 3170, C07G 1100
Patent
active
041743911
ABSTRACT:
The spiramycin derivatives of the formula: ##STR1## wherein R.sup.1 represents acetyl, propionyl or hydrogen, A represents butenylene or butadienylene (wherein any double bonds present in A are trans), and R.sup.2 represents a group of the formula: ##STR2## wherein Z represents bivalent saturated or unsaturated alkylene of 1 to 6 carbon atoms, Y represents sulphur or oxygen, and R.sup.3 represents alkyl of 1 to 6 carbon atoms, cycloalkyl of 3 to 8 carbon atoms, aryl or aralkyl in which the alkylene moiety is of 1 to 6 carbon atoms and their non-toxic salts possess therapeutic and growth-promoting activity.
REFERENCES:
patent: 3000786 (1961-09-01), Wettstein et al.
patent: 3795669 (1974-03-01), Fujimoto et al.
Chapman Robert F.
Jackson David D.
Lee Glyn E.
Brown Johnnie R.
Hazel Blondel
May & Baker Limited
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