Spin filter perfusion bioreactor (SFPB) cell culture apparatus

Details Spin filter perfusion bioreactor (SFPB) cell culture apparatus Spin filter perfusion bioreactor (SFPB) cell culture apparatus

1990-09-13

1992-06-30

Warden, Robert J.

Chemistry: molecular biology and microbiology

Apparatus

Differentiated tissue perfusion or preservation apparatus

435286, 435311, 435312, 435313, 435314, 435315, C12M 300

Patent

active

051262690

ABSTRACT:
An apparatus is disclosed that separates and removes to an external source, spent cell culture media from a cell culture media and cell culture mixture. The apparatus generally comprises a culture vessel, a filter member, wherein the filter member is positioned in the culture vessel to form an outside region and an inside region. Further provided is a tube member. The tube member being positioned in the inside region and having an opening therein to thereby remove the spent cell culture media brought into the inside region. Further disclosed is a structure for rotating the filter member around the tube member and a structure for sealing the outside region from the inside region when the filter member is rotating around the tube member.

REFERENCES:
patent: 3172235 (1965-03-01), Bjorklund
patent: 3186917 (1962-04-01), Gerhardt et al.
patent: 3647632 (1968-04-01), Johnson et al.
patent: 4535062 (1985-08-01), Muller
patent: 4649118 (1987-03-01), Anderson
S. A. Weiss et al., "Cell Culture Methods for Large-Scale Propagation of Baculoviruses", 1986.
The Virtis Company, Gardiner, N.Y., Technical Catalog for Product (Model #240887) entitled "Virtis Biospin Dynamic Filter", 2 color sheets, date of publication is unknown.
S. A. Weiss et al., "Techniques in Setting Up and Maintenance of Tissue and Cell Cultures", Techniques in the Life Sciences, C110, (1985), (16 pages).

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