Spin encapsulation apparatus and method of use

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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435 11, 435177, 435178, 435179, 435180, 435182, 435366, 435382, 623 11, 425 8, 425 10, 425804, 264 4, 264 7, 264 8, 264DIG37, A61F 202, A01N 102, C12N 1102, B29C 3910

Patent

active

056435940

ABSTRACT:
A coating apparatus includes a rotary cup for forming beads and projecting them radially outwardly, and one or more collection basins surrounding the bead forming cup. The cup is adjustably rotatable about its central axis, and the collection basins are independently rotatable and positioned to collect the beads projected from the cup. The coating apparatus further includes an elevation adjustment system for axially adjusting the alignment of the cup with respect to the selected collection basins. The rotational speeds of the cup and the collection basins are selected so as to minimize the impact of the beads against a gelling solution in the collection basins. In use, a supply mixture is introduced into a mixing chamber of the cup. As the cup spins, the coated particles are propelled upwardly by the centrifugal force from the mixing chamber along the inner surface of the cup, and are projected radially outwardly, as beads, into the gelling solution in one of the selected basins. Since the cup and the basin are simultaneously rotated, the impact of the beads against the capture solution is significantly reduced.

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