Sphingosine kinase inhibitors

Details Sphingosine kinase inhibitors Sphingosine kinase inhibitors

2007-05-22

2007-05-22

Spivack, Phyllis G. (Department: 1614)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S369000, C514S370000

Reexamination Certificate

active

10462954

ABSTRACT:
The invention relates to compositions and methods for inhibiting sphingosine kinase and for treating hyperproliferative disease.

REFERENCES:
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patent: 00/17175 (2000-03-01), None
patent: 01/64674 (2001-09-01), None
patent: 01/74793 (2001-10-01), None
Zimenkovsky et al., Fiziologichno Aktivni Rechovini, 2, (2002) 58-64.
Caceres-Dittmar et al., Clinical and Experimental Immunology, (1993), 91(3), pp. 500-505.
Rubbert et al., International Journal of Cancer, (1991), 49(1), pp. 25-31 (abstract).
Perfetti et al., Experimental Hematology, (1991), 19(6), pp. 549 (abstract).
Kono et al. S-15183a and b, “New Sphingosine Kinase Inhibitors, Produced by a Fungus,”The Journal of Antibiotics,vol. 54, No. 5, 2001, pp. 415-420.

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