Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of...
Reexamination Certificate
2007-05-22
2007-05-22
Saoud, Christine J. (Department: 1647)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
C435S006120, C435S069100, C435S252300, C435S320100, C530S350000, C536S023500
Reexamination Certificate
active
10024019
ABSTRACT:
A novel sphingosine 1-phosphate receptor gene, herein termed sppr, and its splice variants. Sppr is up-regulated in LGL and is useful, for example, in the diagnosis and treatment of certain lymphoproliferative, neurodegenerative and autoimmune diseases.
REFERENCES:
patent: 2003/0119111 (2003-06-01), Lal et al.
patent: 1 149 907 (2001-10-01), None
patent: WO 97/00952 (1997-01-01), None
patent: WO 99/33972 (1999-07-01), None
patent: WO 99/46277 (1999-09-01), None
patent: WO 00/11166 (2000-03-01), None
patent: WO 00/31258 (2000-06-01), None
patent: WO 01/66742 (2001-09-01), None
Chen et al. (2002). Discordant protein and mRNA expression in lung adenocarcinomas. Molecular and Cellular Proteomics. 1:304-313.
Haynes et al. (1998). Proteome analysis: biological assay or data archive? Electrophoresis. 19:1862-1871.
Hu et al. (2003). Analysis of genomic and proteomic data using advanced literature mining. Journal of Proteome Research. 2:405-412.
Im et al., D.S., “Characterization of a Novel Sphingosine 1-Phosphate Receptor, Edg-8,”The Journal of Biological Chemistry, vol. 275, No. 19, Issue of May 12, 2000, pp. 14281-14286.
Malek et al., R., “Nrg-1 Belongs to the Endothelial Differentiation Gene Family of G Protein-coupled Sphingosine-1-phosphate Receptors,”The Journal of Biological Chemistry, vol. 276, No. 8, Issue of Feb. 23, 2001, pp. 5692-5699.
Im et al., D.S., “Characterization of the Human and Mouse Sphingosine 1-Phosphate Receptor, SIP5(Edg-8): Structure—Activity Relationship of Sphingosine1-Phosphate Receptors,”Biochemistry 2001, vol. 40, pp. 14053-14060.
Kothapalli et al., R., Characterization of a Novel Human Sphingosine-1-Phosphate Receptor Gene (sppr) and Its Differential Expression in LGL Leukemia, submitted to BBA on Aug. 9, 2001.
Kothapalli et al., R., “Characterization of a Novel Human Sphingosine-1-Phosphate Receptor Gene (sppr) and Its Differential Expression in LGL Leukemia,”Blood: Gene Expression in Lymphoid Malignancy, Nov. 2001, vol. 98, p. 3029.
Im et al., D.S., as cited in: “1:NM—030760.Homo sapiens endo . . . ”.
Kothapalli et al., R., as cited in: “1:AF331840.Homo sapiens SPPR . . . ”.
Kothapalli et al., R., as cited in: “1:AF331841.Homo sapiens SPPR . . . ”.
Im et al., D.S., as cited in: “1:NM—030760[gi:13540516]”.
Kothapalli et al., R., as cited in: “1:AF331842.Homo sapiens SPPR . . . ”.
Database EMBL ′ONLINE! Oct. 8, 1999, retrieved from EBI Database accession No. ACO11461 XP002236899 abstract.
Database EMBL ′ONLINE! Sep. 28, 2001, retrieved from EBI Database accession No. AX244600 XP002236900 abstract (Sequence 26 from Patent WO 01 66742).
Database EMBL ′ONLINE! Dec. 6, 2000, retrieved from EBI Database accession No. af317676 XP002236901 abstract.
An et al., “Signaling Mechanisms and Molecular Characteristics of G Protein-Coupled Receptors for Lysophosphatidic Acid and Sphingosine 1-Phosphate”,Journal of Cellular Biochemistry Supplements(1998), 31:147-157.
Im et al., “Characterization of a Novel Sphingosine 1-Phosphate Receptor, Edg-8*”,The Journal of Biological Chemistry(2000), 275(19): 14281-14286.
Hla et al., “Sphingosine-1-Phosphate Signaling via the EDG-1 Family of G-Protein-Coupled Receptors”,Annals New York Academy of Sciences(2000), 905:16-24.
Glickman et al., “Molecular Cloning, Tissue-Specific Expression, and Chromosomal Localization of a Novel Nerve Growth Factor-Regulated G-Protein-Coupled Receptor,nrg-1”,Molecular and Cellular Neuroscience(1999), 14: 141-152.
An et al., “Characterization of a Novel Subtype of Human G Protein-Coupled Receptor for Lysophosphatidid Acid*”,The Journal of Biological Chemistry(1998), 273(14): 7906-7910.
Kothapalli et al., “Characterization of a Human Sphingosine-1-Phosphate Receptor Gene (S1P5) and its Differential Expression in LGL Leukemia”,Biochimica et Biophysica Acta(2002), 117-123.
Semenzato et al., The Lymphoproliferative Disease of Granular Lymphocytes: Updated Criteria for Diagnosis,Blood(1997), 89(1): 256-260.
Epstein and Butow, “Microarray technology- enhanced versatility, persistent challenge”,Current Opinion in Biotechnology(2000), 11: 36-41.
Kothapalli Ravi
Loughran, Jr. Thomas P.
Lockard Jon M.
Saliwanchik Lloyd & Saliwanchik
Saoud Christine J.
University of South Florida
LandOfFree
Sphingosine 1-phosphate receptor gene, sppr does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Sphingosine 1-phosphate receptor gene, sppr, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Sphingosine 1-phosphate receptor gene, sppr will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3764278